Cat. No.

CBCRY29

Background

Cytochrome c, or cyt c is a small heme protein found loosely associated with the inner membrane of the mitochondrion. It belongs to the cytochrome c family of proteins. Cytochrome c is a highly soluble protein, unlike other cytochromes, with a solubility of about 100g/L and is an essential component of the electron transport chain, where it carries one electron. It is capable of undergoing oxidation and reduction, but does not bind oxygen.

Molecular description

Protein Classification

Electron Transport

Structure Weight

12541.14 Da

Polymer

1

Molecule

Cytochrome c, testis-specific

Chain Length

105 amino acids

Crystal Description

PDB ID

2AIU

MMDB ID

40235

Source

E.coli

Method

X-Ray Diffraction

Resolution

1.6Å

Ligand Chemical Component

HEM; phosphate ion

Gene information

Gene Name

Cyct

Synonyms

RP23-211L7.1; T-Cc; OTTMUSP00000014130

GeneID

13067

Chromosome  Location

2 47.0 cM

Function

iron ion binding; electron carrier activity; heme binding; metal ion binding

Reference

Liu, Z.,  Lin, H.,  Ye, S.,  Liu, Q.Y.,  Meng, Z.,  Zhang, C.M.,  Xia, Y.,  Margoliash, E.,  Rao, Z.,  Liu, X.J. (2006) Remarkably high activities of testicular cytochrome c in destroying reactive oxygen species and in triggering apoptosis Proc.Natl.Acad.Sci.Usa 103: 8965-8970