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Iterative Crystallography Service at Creative Biostructure

Featuring staffed with leading scientists and equipped with state-of-the-art facilities in the field of structural biology, Creative Biostructure has established a high-performance and ready-to-go platform for iterative crystallography service.

We have determined a number of crystal structures for the proteins playing important roles in various signal pathways involved in cell proliferation, development and differentiation. We have extensive experiences in co-crystallizing complex proteins with compounds and ligands. Examples of the crystal structures are listed below. For more details, please inquire us via Email: info@creative-biostructure.com or Tel: 1-866-588-6325.
 

The Protein List for Iterative Crystallization

Cat#

Gene Symbol

cDNA length [bp]

Fragment

Protein Description

CBCRY01

BUB1

1095

Residues 724-1085

Mitotic checkpoint serine/threonine-protein kinase BUB1

CBCRY02

MAD2

618

Full length

Mitotic arrest deficient 2

CBCRY03

MAD2 with p31

630 (MAD2)

Full length

Mad2 complexed with p31(comet)

804 (MAD2L1BP)

Residues 36-274

CBCRY04

LSD1 with CoREST

1998 (LSD1)

Residues 171-836

Lysine-specific histone demethylase1 complexed with REST corepressor1

705 (CoREST)

Residues 308-482

CBCRY05

3CLpro

918

Full length

SARS Coronavirus Main Proteinase Complexed With Inhibitor

CBCRY06

FCAR

651

Residues 0-217

Extracellular fragment of Fc alpha Receptor I (CD89)

CBCRY07

Eed

1083

Residues 81-441

Embryonic Ectoderm Development

CBCRY08

Kv4.3 with KChIP1

540 (KCNIP1)

N-terminal domain

Potassium channel Kv4.3 complexed with regulatory subunit KChIP1

420 (KCNA3)

Residues 6-145

CBCRY09

WDR5

933

Residues 24-334

WD-repeat protein 5

CBCRY10

IDI1

765

Full length

Isopentenyl-diphosphate delta-isomerase 1

CBCRY11

PGAM1

786

Full length

Phosphoglycerate Mutase 1

CBCRY12

EIF3K

750

Full length

Eukaryotic translation initiation factor 3 subunit K

CBCRY13

BPGM

813

Full length

2,3-bisphosphoglycerate mutase

CBCRY14

CRYM

936

Full length

Mu-crystallin homolog

CBCRY15

COTL1

435

Full length

Coactosin-like protein

CBCRY16

THEM2

528

Full length

Thioesterase superfamily member 2

CBCRY17

GMPR2

1098

Full length

Guanosine monophosphate reductase 2

CBCRY18

NTF3 with NGFR

357 (NTF3)

Ectodomain

Neurotrophin-3 complexed with NTR receptor

501 (NGFR)

CBCRY19

PDXK

981

Full length

Pyridoxal kinase

CBCRY20

CLIC4

783

Full length

Chloride intracellular channel 4

CBCRY21

SAT1

537

Full length

Diamine Acetyltransferase 1

CBCRY22

DEBP

834

Residues 24-302

Periplasmic Binding Transport Protein

CBCRY23

AR

750

Residues 669-918

Androgen Receptor

CBCRY24

PBGD

1092

Full length

Porphobilinogen deaminase

CBCRY25

PYCR2

831

Full length

Pyrroline-5-carboxylate Reductase 2

CBCRY26

MASA

855

Full length

Enolase-phosphatase E1

CBCRY27

PYCR1

963

Full length

Pyrroline-5-carboxylate Reductase 1

CBCRY28

ARHGEF7

183

SH3 domain

Rho Guanine Nucleotide Exchange Factor 7

CBCRY29

Cyct

315

Full length

Cytochrome c, Testis-specific

CBCRY30

GPD1

1062

Full length

Glycerol-3-phosphate Dehydrogenase [NAD+], Cytoplasmic

CBCRY31

DNCL2A

318

Full length

Dynein Light Chain Dnlc2a

CBCRY32

ARTN

315

N-terminal truncated

Neurotrophic Factor Artemin Isoform 3 

CBCRY33

IL2 with IL2RA

399 (IL2)

Extracellular domain

Interleukin-2 complexed with IL2 alpha Receptor

657 (IL2RA)

CBCRY34

PPARG

888

Ligand binding domain

Peroxisome Proliferator-activated Receptor Gamma

CBCRY35

USP7

1566

Residues 43-560

Ubiquitin Carboxyl-terminal Hydrolase 7

CBCRY36

ALB

1674

Full length

Serum Albumin

CBCRY37

PABPN1

288

UNP residues 167-254

Polyadenylate-binding Protein 2

CBCRY38

VPS29

546

Full length

Vacuolar Protein Sorting Protein 29

CBCRY39

CASP3

759

Full length

Caspase-3
 

The Protein List for Iterative Crystallization 2

Cat#

Gene Symbol

Resolution

Protein Description

CBCRY40

MARK1

2.9 A

MAP/microtubule Affinity-regulating Kinase 1

CBCRY41

MARK2

3.0 A

MAP/microtubule Affinity-regulating Kinase 2

CBCRY42

MARK3

2.9 A

MAP/microtubule Affinity-regulating Kinase 3

CBCRY43

MARK4

1.8 A

MAP/microtubule Affinity-regulating Kinase 4

CBCRY44

PKN B

2.0 A

Protein Kinase B

CBCRY45

PI3Kα

3.0 A

Phosphoinositide 3 Kinase Alpha

CBCRY46

BCL_XL

2.1 A

BCL_XL

CBCRY47

DAAO3

1.8 A

D-amino Acid Oxidase 3

CBCRY48

GSK3b

2.5 A

Glycogen Synthase Kinase 3 beta

CBCRY49

PDE 2

1.7 A

Phosphodiesterase 2

CBCRY50

EphA2

2.6 A

EPH Receptor A2

CBCRY51

PDE 10

1.8 A

Phosphodiesterase 10

CBCRY52

PAK1

1.9 A

P21/Cdc42/Rac1-activated kinase 1

CBCRY53

PAK1

2.2 A

P21/Cdc42/Rac1-activated kinase 1

CBCRY54

PTP1B

2.3 A

Protein Tyrosine Phosphatase, Non-receptor Type 1

CBCRY55

PLK1

2.8 A

Polo-like Kinase 1

CBCRY56

PLK2

2.9 A

Polo-like Kinase 2

CBCRY57

PLK3

2.5 A

Polo-like Kinase 3

CBCRY58

PLK4

2.2 A

Polo-like Kinase 4

CBCRY59

SET7/9

2.2 A

SET Domain Containing (Lysine Methyltransferase) 7