-> The Library Screening solution utilizes our broad portfolio of biochemical and cell based assays to meet the demands of your current library screening projects, to search the novel hits, and move forwrad the hit-to-lead process in high quality and efficiency.
-> The Library Screening solution allows you to send your in-house assay or choose from hundreds of validated assays for key target classes including kinases, GPCRs, P450s, nuclear receptors and ion channels. Rongene can perform validation and screen the client's assays by customized technologies, or build a custom assay to fit your specific screening needs.
-> There are more than 200 screening models, including over 100 High Throughput Screening (HTS) and High Content Screening (HCS) models in 96-well plate or 384-well plate formats. We have collaborated with hundreds of drug discovery firms including pharmaceuticals, institutes, and universities, and provided the high quality and cost-effective solutions and consultancy. Some of these lead compounds have been patented and developed into preclinical and clinical phase.
-> Support of iterative optimization cycles in MedChem
-> G-Protein Coupled Receptors (GPCR)
-> Nuclear receptors (steroidal and non-steroidal)
-> Ion Channels
-> Cytochrome P450 enzyme
->Other enzymes, cholinesterases, polymerases, proteases, transferases and phosphodiesterases, including anhydrases, esterases, hydrolases, oxidases, oxygenases, reductases, secretases, synthases, phospholipases, ATPases