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PBGD Protein Crystal(CBCRY24)

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Product Summary
Name PBGD Protein Crystal
Download Datasheet
Cat No.CBCRY24
FragmentFull length
Protein DescriptionPorphobilinogen deaminase
BackgroundThe protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.
Protein ClassificationTransferase
Structure Weight80152.23 Da
MethodX-Ray Diffraction
Resolution2.18Å
Ligand Chemical ComponentDPM
ReferenceSong, G., Li, Y., Cheng, C., Zhao, Y., Gao, A., Zhang, R., Joachimiak, A., Shaw, N., Liu, Z.J. (2009) Structural insight into acute intermittent porphyria. Faseb J. 23: 396-404

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