Creative Biostructure to Present at AACR Annual Meeting 2024 Creative Biostructure to Present at AACR Annual Meeting 2024 | April 5-10, 2024 | Booth #2953 Learn More > Close

FCAR Protein Crystal(CBCRY06)

Inquiry
Product Summary
Name FCAR Protein Crystal
Download Datasheet
Cat No.CBCRY06
FragmentResidues 0-217
Protein DescriptionExtracellular fragment of Fc alpha Receptor I (CD89)
BackgroundHuman FcalphaRI (CD89) is the receptor specific for IgA, an immunoglobulin that is abundant in mucosa and is also found in high concentrations in serum. Although FcalphaRI is an immunoglobulin Fc receptor (FcR), it differs in many ways from FcRs for other immunoglobulin classes. The genes of most FcRs are located on chromosome 1 at 1q21-23, whereas FcalphaRI is on chromosome 19, at 19q13.4, a region called the leukocyte receptor complex, because it is clustered with several leukocyte receptor families including killer cell inhibitory receptors (KIRs) and leukocyte Ig-like receptors (LIRs). The amino acid sequence of FcalphaRI shares only 20% homology with other FcRs but it has around 35% homology with its neighboring LIRs and KIRs.
Protein ClassificationImmune System
Structure Weight25006.40 Da
MethodX-Ray Diffraction
Resolution2.1 Å
ReferenceDing, Y., Xu, G., Yang, M., Yao, M., Gao, G.F., Zhang, W., Rao, Z. Crystal Structure of the Ectodomain of Human Fc{alpha}RI.J.Biol.Chem. 2003; 278: 27966-27970

Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Inquiry