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PLK2 Protein Crystal(CBCRY54)

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Product Summary
Name PLK2 Protein Crystal
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Cat No.CBCRY54
FragmentPolo box domain
Protein DescriptionPolo-like Kinase 2
BackgroundPolo-like kinase 2 (PLK2) is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division. This gene is most abundantly expressed in testis, spleen and fetal tissues, and its expression is inducible by serum, suggesting that it may also play an important role in cells undergoing rapid cell division. Polo-like kinases are the key regulators of cell cycle progression, the members of which share a kinase domain and a polo-box domain that serves as a protein-binding module.
Protein ClassificationTransferase
Structure Weight50489.28 Da
MethodX-Ray Diffraction
Resolution2.70 Å
Ligand Chemical ComponentPO4-,Cl-
ReferenceKim JH, Ku B, Lee KS, Kim SJ. Structural analysis of the polo-box domain of human polo-like kinase 2. Proteins (2015)

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