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PYCR1 Protein Crystal(CBCRY27)

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Product Summary
Name PYCR1 Protein Crystal
Download Datasheet
Cat No.CBCRY27
FragmentFull length
Protein DescriptionPyrroline-5-carboxylate Reductase 1
BackgroundPyrroline-5-carboxylate reductase (P5CR) is a universal housekeeping enzyme that catalyzes the reduction of Delta(1)-pyrroline-5-carboxylate (P5C) to proline using NAD(P)H as the cofactor. The enzymatic cycle between P5C and proline is very important for the regulation of amino acid metabolism, intracellular redox potential, and apoptosis.
Protein ClassificationOxidoreductase
Structure Weight168155.50 Da
MethodX-Ray Diffraction
Resolution3.1Å
ReferenceMeng, Z., Lou, Z., Liu, Z., Li, M., Zhao, X., Bartlam, M., Rao, Z. (2006) Crystal structure of human pyrroline-5-carboxylate reductase J.Mol.Biol. 359: 1364-1377

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