Creative Biostructure provides virus-like particles (VLPs) containing high concentrations of specific membrane proteins in their native conformation. VLPs capture conformationally-intact membrane proteins directly from the cell surface, enabling these complex proteins to be manipulated as soluble proteins. Our VLPs are produced with specified membrane proteins on a custom basis, or are available from a selected catalog of ReadyVLPs. Sample kits are also available for purchase for preliminary application testing.
VLPs provide an alternative to living cells, membrane preparations, and detergent-solubilized proteins by offering concentrated membrane proteins in their native conformation. VLPs are used throughout drug and antibody discovery and characterization, and have been integrated into a wide variety of existing platforms.
Epitope tags: N=amino terminal, C=carboxy terminal Lipoparticles can be modified with (B) Biotin or (F) Fluorescence
Creative Biostructure holds good stocks of all our antigens to ensure a rapid delivery service worldwide. Using our optimized production process, custom VLPs are engineered to incorporate high concentrations of specified membrane proteins. This process includes optimization of membrane protein expression and incorporation. We like to be in touch with our customers so please feel free to contact us for a formal quote.