Backed by years of expertise in exosome research and development, Creative Biostructure is committed to providing comprehensive solutions that meet the diverse needs of your project. Our services include:
We offer high-purity exosome isolation from diverse sources using ultracentrifugation, SEC, TFF, and immunoaffinity methods for research and downstream industrial applications.
We provide comprehensive exosome characterization, including surface markers, morphology, size, cargo profiling, purity, and stability using advanced technologies for reliable quality assessment.
We offer integrated exosome multi-omics analysis, including RNA sequencing, proteomics, lipidomics, and metabolomics to support biomarker discovery and functional mechanism studies.
We provide customizable exosome engineering services, including surface modification, cargo loading, and advanced labeling to enhance delivery, targeting, and tracking capabilities.
We offer comprehensive in vitro and in vivo exosome functional assays to evaluate bioactivity, drug delivery, immune response, cell interaction, and therapeutic potential.
We provide GMP-compliant exosome production, covering upstream process development, cell culture optimization, and downstream purification, ensuring high-quality exosomes for diverse applications.
At Creative Biostructure, we offer state-of-the-art exosome purification and characterization technologies to enhance your project.
Creative Biostructure offers tailored exosome solutions across industries, including drug discovery, diagnostics, skincare, nutraceuticals, and regenerative medicine, with specialized applications in delivery and biomarkers.
Exosomes are biocompatible, low-immunogenic nanocarriers ideal for delivering therapeutic molecules. We offer tailored solutions for RNA (siRNA, miRNA, mRNA, circRNA), ASO, protein, peptide, and small molecule delivery, ensuring efficient loading, stability, and targeting for research use.
Example: Delivering tumor-targeted siRNA via exosomes → enhancing gene silencing efficiency and reducing off-target effects.
We provide exosome-based solutions to support non-invasive diagnostics and biomarker discovery. We offer services for exosomal RNA/protein profiling, liquid biopsy, companion diagnostics, and custom biomarker panels to accelerate early disease detection and precision medicine.
Example: Profiling exosomal miRNAs via liquid biopsy → enabling non-invasive cancer diagnosis and early biomarker detection.
Our solutions include exosome-based vaccine development, immunomodulation, inflammation control, wound healing, and bone regeneration studies, enabling preclinical validation of novel therapeutic strategies.
Example: Developing exosome-based vaccines for infectious diseases → improving antigen presentation and immune response.
We provides cosmetic-grade exosome solutions derived from stem cells and plants to support skincare innovation. Our services include exosome sourcing, formulation development, and comprehensive safety and efficacy testing to accelerate the development of next-generation cosmetic products.
Example: Applying plant-derived exosomes in cosmetic formulations → enhancing skin hydration, barrier repair, and overall skin health.
We provide services for developing edible exosomes from plants and milk to support functional food innovation. Our solutions include gut absorption studies, stability testing, and bioavailability assessments.
Example: Delivering vitamins, minerals, and polyphenols via plant-derived exosomes → improving stability, bioavailability, and targeted nutrient absorption.
Proven by successful collaborations with global scientists advancing exosome research, analytics, and application development.
"Visual confirmation of exosome morphology was vital for our study, and Creative
Biostructure delivered precisely what we needed. Their high-resolution TEM
imaging enabled us to confidently verify the integrity of hucMSC-derived
exosomes, laying a strong foundation for our downstream mechanistic
investigations into cardioprotection."
— Dr. Ming Luo, Tongji University
School of Medicine
Problem Solved: Validating the morphology and structural integrity of hucMSC-derived exosomes prior to functional assays.
Solution: Creative Biostructure provided high-quality TEM imaging services that confirmed the presence and morphology of purified exosomes, ensuring reliable data for further biological analysis.
Publication: Liang C, Liu Y, Xu H, et al. Exosomes of human umbilical cord MSCs protect against hypoxia/reoxygenation-induced pyroptosis of cardiomyocytes via the miRNA-100-5p/FOXO3/NLRP3 pathway. Frontiers in Bioengineering and Biotechnology. 2021, 8: 615850.
"Creative Biostructure's precise fatty acid analysis played a pivotal role in
our extracellular vesicle research. Their accurate quantification enabled us to
characterize lipid profiles in EVs isolated from human milk, supporting our
study's compliance with MISEV guidelines and enriching our understanding of
milk-derived bioactive components."
— Dr. John Miklavcic, Chapman
University
Problem Solved: Difficulty in quantifying lipid content in low-volume EV samples from human milk.
Solution: Creative Biostructure performed high-sensitivity fatty acid analysis, allowing reliable lipid profiling across EV isolation variations.
Publication: Bickmore D C, Miklavcic J J. Characterization of extracellular vesicles isolated from human milk using a precipitation-based method. Frontiers in Nutrition. 2020, 7: 22.
Trusted by global researchers and institutions for exosome solutions in drug delivery, biomarker discovery, and formulation development.
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