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CaS receptor VLP

(CBS-V003)  Download Datasheet
Name
CaS receptor VLP
Cat No.
CBS-V003
Virus Family
Retrovirus
Composition
Calcium Sensing receptor, Gag protein
Source
Insect recombinant
Protein Conc.
0.6-1.0 mg/mL
Purity
>95% by SDS-PAGE
Presentation
PBS, pH 7.8
Description
The protein is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.

We provide highly purified Virus-Like Particles (VLPs) products as antigens, produced in a native format, mostly using a mammalian expression system. Custom VLPs synthesis is also offered presented as a cell lysate or a purified antigen for use in vaccine development (including use as an immunogen) and serological based diagnostic assays. We like to be in touch with our customers so please feel free to contact us for a formal quote.

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