- Name
- CCR1 VLP
- Cat No.
- CBS-V004
- Virus Family
- Retrovirus
- Composition
- C-C motif chemokine receptor 1, Gag protein
- Source
- Mammalian recombinant
- Protein Conc.
- 1.0-1.5 mg/mL
- Purity
- >95% by SDS-PAGE
- Presentation
- Phosphate buffered saline at pH 7.4.
- Description
- This protein is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
We provide highly purified Virus-Like Particles (VLPs)
products as antigens, produced in a native format, mostly using a mammalian expression system. Custom VLPs synthesis is also offered presented as a cell lysate or a purified antigen for use in vaccine development (including use as an immunogen) and serological based diagnostic assays. We like to be in touch with our customers so please feel free to contact us for a formal quote.
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