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Name
CCR10 VLP
Cat No.
CBS-V010
Virus Family
Retrovirus
Composition
Rhesus monkey C-C motif chemokine receptor 10, Gag protein
Source
Insect recombinant
Protein Conc.
0.5-1.0 mg/mL
Purity
>95% by SDS-PAGE
Presentation
20mM Tris-HCl, pH 7.5, 250 mM NaCl.
Description
CCR10 is a chemokine receptor. Its ligands are CCL27 and CCL28. This receptor is normally expressed by melanocytes, plasma cells and skin-homing T cells. B16 melanoma cell transduction of CCR10 significantly increases the development of lymph node metastasis in mice after inoculation in the skin, suggesting a role for the receptor in directing metastasis. CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation.

We provide highly purified Virus-Like Particles (VLPs) products as antigens, produced in a native format, mostly using a mammalian expression system. Custom VLPs synthesis is also offered presented as a cell lysate or a purified antigen for use in vaccine development (including use as an immunogen) and serological based diagnostic assays. We like to be in touch with our customers so please feel free to contact us for a formal quote.

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