Creative Biostructure

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Name
CD27 VLP
Cat No.
CBS-V030
Virus Family
Retrovirus
Composition
CD27 molecule, Gag protein
Source
Insect recombinant
Protein Conc.
0.5-1.0 mg/mL
Purity
>95% by SDS-PAGE
Presentation
20mM Tris-HCl, pH 7.5, 250 mM NaCl.
Description
The protein is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.

We provide highly purified Virus-Like Particles (VLPs) products as antigens, produced in a native format, mostly using a mammalian expression system. Custom VLPs synthesis is also offered presented as a cell lysate or a purified antigen for use in vaccine development (including use as an immunogen) and serological based diagnostic assays. We like to be in touch with our customers so please feel free to contact us for a formal quote.

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