Creative Biostructure

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Name
DR5 VLP
Cat No.
CBS-V036
Virus Family
Retrovirus
Composition
TNF receptor superfamily member 10b, Gag protein
Source
Insect recombinant
Protein Conc.
0.6-1.0 mg/mL
Purity
>95% by SDS-PAGE
Presentation
Tris-HCl, pH 7.5
Description
The protein is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

We provide highly purified Virus-Like Particles (VLPs) products as antigens, produced in a native format, mostly using a mammalian expression system. Custom VLPs synthesis is also offered presented as a cell lysate or a purified antigen for use in vaccine development (including use as an immunogen) and serological based diagnostic assays. We like to be in touch with our customers so please feel free to contact us for a formal quote.

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