Creative Biostructure

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Name
GLP-1R VLP
Cat No.
CBS-V016
Virus Family
Retrovirus
Composition
Glucagon-like peptide-1 Receptor, Gag protein
Source
Insect recombinant
Protein Conc.
0.6-1.0 mg/mL
Purity
>95% by SDS-PAGE
Presentation
Tris-HCl, pH 7.5
Description
This is a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.

We provide highly purified Virus-Like Particles (VLPs) products as antigens, produced in a native format, mostly using a mammalian expression system. Custom VLPs synthesis is also offered presented as a cell lysate or a purified antigen for use in vaccine development (including use as an immunogen) and serological based diagnostic assays. We like to be in touch with our customers so please feel free to contact us for a formal quote.

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