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Name
mCXCR4 VLP
Cat No.
CBS-V015
Virus Family
Retrovirus
Composition
Mouse C-X-C motif chemokine receptor 4, Gag protein
Source
Mammalian recombinant
Protein Conc.
1.0-1.5 mg/mL
Purity
>95% by SDS-PAGE
Presentation
20mM Tris-HCl, pH 7.5, 250 mM NaCl.
Description
CXCR4 is a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

We provide highly purified Virus-Like Particles (VLPs) products as antigens, produced in a native format, mostly using a mammalian expression system. Custom VLPs synthesis is also offered presented as a cell lysate or a purified antigen for use in vaccine development (including use as an immunogen) and serological based diagnostic assays. We like to be in touch with our customers so please feel free to contact us for a formal quote.

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