Studies Revealed the Cryo-EM structure of Human Lysosomal Cobalamin Exporter ABCD4

Recently, Yuxing, Chen and Congzhao, Zhou, professors of National Research Center for Microscale Material Science and Department of Life Science and Medicine of University of Science and Technology of China, collaborated with Linfeng Sun’s group to analyze the near-atomic resolution 3D structure of human lysosomal vitamin B12 efflux protein ABCD4 using cryo-EM technology for the first time, providing a basis for in-depth understanding of the molecular mechanism of this type…

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