Three-Dimensional Structures of the Herpesvirus HSV-1/HSV-2 Capsid Revealed

HSV Capsid

Herpesvirus is one of the most complex viruses both genetically and structurally. It spreads efficiently to host populations and leads to a range of human diseases, including congenital defects and cancers.   The herpesvirus assembly pathway produces three different types of capsids: A-, B-, and C-capsids. All three capsid types have a mature, angled shell and a similar assembly mechanism. However, little is known about the structure and assembly mechanism…

Read More >>