Advanced Genome Mining for Coronavirus

As an expert in data analysis, Creative Biostructure is helping our customers with genomic data analysis services for coronavirus research. We have rich experience in solving special analyses of various viral genomes, and our customer-centric bioinformatics analysis team guarantees high-quality analytical data for customers worldwide.

Application of Genomic Data Analysis in Coronavirus Research

Antigen Design and Preparation Services for Coronavirus

The large-scale spread of novel coronavirus (also known as SARS-CoV-2) in humans has attracted the attention of global public health institutions and scientific research institutions. High-throughput sequencing technology is a powerful tool for studying emerging infectious diseases such as SARS, MERS, Zika, Ebola, and COVID-19, which pose serious threats to global health and the economy. Early in the outbreak of COVID-19, researchers sequenced the genome of bronchoalveolar lavage fluid (lung secretions) collected from patients and identified a novel virus. And it found out that the viral genome has 89.1% similarity to that of bat SARS-like coronavirus. The data sharing of the whole genome sequence of multiple strains of SARS-CoV-2 helps global scientists to carry out viral molecular epidemiological studies. The continuous development of high-throughput sequencing and bioinformatics technologies will greatly accelerate the genome sequencing and data analysis of emerging viruses, laying the foundation for more effective epidemic prevention and more comprehensive real-time monitoring of viruses.

Advanced Genome Mining Services for Coronavirus Research

Data mining based on genome sequence is of significance for the identification and phylogenetic analysis of novel viruses. In addition, the virus is likely to mutate during transmission, and the novel coronavirus is no exception, thus the monitoring of virus mutation becomes particularly important. Professional bioinformatics analysis team of Creative Biostructure supports the following genomic data analysis services for coronavirus research, including but not limited to:

  • Genome Resequencing Data Analysis
  • Sequencing quality assessment, Sequencing data splicing, Genome annotation, Detection of SNP and CNV, Functional analysis of mutant genes, as well as Network analysis of mutant genes

  • De Novo Sequencing Data Analysis
  • Sequencing quality assessment, Sequencing data splicing, Gene prediction, Functional annotation of genes, KEGG annotation, Comparative genomic analysis, Sequential evolution analysis, Phylogenetic tree building and analysis

  • Specific Analyses of Viral Genomes
  • Prediction of pathogenicity/genomic islands, Analysis of virus-specific and conserved fragments of the genome, Graphical display of the genome, Analysis of the correlation between the pattern of virus mutation and virus resistance, Evolutionary analysis of crucial genes

We do not provide diagnostic services and the service is only appropriate for research purposes. Our customer service representatives are available 24 hours a day from Monday to Sunday, and you can contact us at any time to discuss your coronavirus-related project.

Contact us to discuss your project!

References

  1. Zhou P.; et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020: 1-4.
  2. Sah R.; et al. Complete genome sequence of a 2019 novel coronavirus (SARS-CoV-2) strain isolated in Nepal. Microbiology Resource Announcements. 2020, 9(11).

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