Our promise to you: Guaranteed product quality, expert customer support.

GMPR2 Protein Crystal(CBCRY17)

Product Summary
Name GMPR2 Protein Crystal Download Datasheet
Background Guanosine monophosphate reductase (GMPR) Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. Plays a role in modulating cellular differentiation.
Molecular Description
Protein ClassificationOxidoreductase
Structure Weight161477.73 Da
MoleculeGMP reductase 2
Chain Length366 amino acids
Crystal Description
MMDB ID37032
MethodX-Ray Diffraction
Resolution3.0 Å
Ligand Chemical Componentguanosine-5'-monophosphate; sulfate ion
Gene Information
Gene NameGMPR2
SynonymsMGC15084; MGC830; GMP reductase 2; guanosine 5'-monophosphate oxidoreductase 2; guanosine monophosphate reductase isolog; EC
UniProt IDQ9P2T1
Gene ID51292
Chromosome Location14q12
FunctionGMP reductase activity; metal ion binding; oxidoreductase activity; potassium ion binding
Reference Li, J., Wei, Z., Zheng, M., Gu, X., Deng, Y., Qiu, R., Chen, F., Ji, C., Gong, W., Xie, Y., Mao, Y. (2006) Crystal Structure of Human Guanosine Monophosphate Reductase 2 (GMPR2) in Complex with GMP J.Mol.Biol. 355: 980-988

Online Inquiry

  • Verification code
    Click image to refresh the verification code.