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Citations

Publications, Patents, and Book Chapters Citing Our Work

We provided high-quality service to numerous customers. A long list of papers have been published in Peer-reviewed Publications journals and a lot of patent applications have been approved or in process with custom products or services from us. Below are some selected patents and papers to give you an idea of how our products and custom services have been applied as part of leading edge in life science research in academia and industry. These publications are sorted according to different divisions of our company.

 

  • Peer-reviewed Publications
  • Patents
  • Book Chapters
  1. Jankelow, Aaron, et al. "Multiplexed electrical detection of whole viruses from plasma in a microfluidic platform." Analyst (2024).

    … B19V virus-like particles (VLPs) (Cat# CBS-V088-C) were obtained from Creative Biostructure

    Related Services/Products:

    Parvovirus B19 VLP (VP1, VP2) Co-Capsid

  2. Marino, Claudia, et al. "APOE Christchurch‐mimetic therapeutic antibody reduces APOE‐mediated toxicity and tau phosphorylation." Alzheimer's & Dementia (2023).

    … Recombinant Fab region including the complementarity-determining regions (CDRs) of the 7C11.chIgG1 antibody was produced as fee-for-service by Creative BioStructure (Shirley, NY, USA) … … Binding kinetics between the purified Fab-7C11 protein and recombinant ApoE4 were quantified in PBS solution using a Biacore 3000 instrument (GE Healthcare) as a fee-for-service with Creative BioStructure and according to previously published procedures … … We resolved the three-dimensional crystal structure of purified 7C11.IgGFab protein as a fee-for-service with Creative BioStructure

    Related Services/Products:

    Custom Protein Production Surface Plasmon Resonance (SPR) X-ray Crystallography Services

  3. Hrušková, Helena, Roman Řemínek, and František Foret. "Offline preparative separation methods based on electromigration: An overview and current trends." TrAC Trends in Analytical Chemistry (2023): 117428.

    … Commercial free-flow electrophoretic instruments, e.g., Free-Flow electrophoresis systems marketed by FFE Service GmbH (Feldkirchen, Germany) or Creative Biostructure (Shirley, NY, USA) …

    Related Services/Products:

    Mempro™ Free Flow Electrophoresis (FFE)

  4. Goc, Anna, et al. "Inhibition of α-hemolysin activity of Staphylococcus aureus by theaflavin 3, 3’-digallate." Plos one 18.8 (2023): e0290904.

    … To determine binding affinity of native Hla with TF3, SPR binding assay was performed (Creative Biostructure, Shirley, NY) …

    Related Services/Products:

    Surface Plasmon Resonance (SPR)

  5. Goc, Anna, et al. "Phytochemicals and micronutrients in suppressing infectivity caused by SARS-CoV-2 virions and seasonal coronavirus HCoV-229E in vivo." European Journal of Microbiology and Immunology (2023).

    … SARS-CoV-2 viral like particles (VLPs) were obtained from Creative Biostructure (Shirley, NY, USA) …

    Related Services/Products:

    SARS-CoV-2 VLP Products

  6. Molla, Mohammad Habibur Rahman, and Mohammed Othman Aljahdali. "Marine-derived sea urchin compounds as potential anti-cancer drug candidate against colorectal cancer: In silico and in vitro studies." Saudi Journal of Biological Sciences 30.9 (2023): 103748.

    … Easily predicting the hydrophobicity, solubility, permeability, etc. of substances and applying predictive models for blood–brain barrier (BBB) permeability, medication bioavailability, cytochrome P450, hERG toxicity, and more are possible using Creative Biostructure

    Related Services/Products:

    ADME-Tox Modeling and Prediction

  7. Kwon, Taek Hun, and Tae Gyun Kim. "Purification, crystallization, and preliminary structural analysis of multivalent immunogenic effector protein-anchored SARS-CoV-2 RBD." bioRxiv (2023): 2023-08.

    … Crystallization BmRecA-RBD protein was initially crystallized using various screening kits from commercial company as Hampton Research, Creative Biostructure

    Related Services/Products:

    Optimization of Screening Kits and Reagents

  8. Kang, IL-Ho, et al. "A novel mechanism of herbicide action through disruption of pyrimidine biosynthesis." Proceedings of the National Academy of Sciences 120.48 (2023): e2313197120.

    Creative Biostructure (Shirley, NY) provided the X-ray crystallographic support …

    Related Services/Products:

    X-ray Crystallography Services

  9. Lodaya, Rushit N., et al. "A Self-Emulsified Adjuvant System Containing the Immune Potentiator Alpha Tocopherol Induces Higher Neutralizing Antibody Responses than a Squalene-Only Emulsion When Evaluated with a Recombinant Cytomegalovirus (CMV) Pentamer Antigen in Mice." Pharmaceutics 15.1 (2023): 238.

    … To understand the morphology of the oil droplets in SE-AS44 compared to AS03, we collaborated with Creative Biostructure (Shirley, NY, USA) to obtain cryo-EM images and size …

    Related Services/Products:

    Particle Morphology Analysis

  10. Somasundaram, Dr N. "A Review on Liposomes as a Drug Delivery System." International Journal of Pharmacy and Analytical Research (IJPAR).Vol-12(3) 2023: 346-357.

    … Known for high performance and efficient development in liposome delivery systems, Creative Biostructure has extended the applications into the cosmetic industry …

    Related Services/Products:

    Liposome Products

  11. Monferrer, Alba, et al. "Broad-spectrum virus trapping with heparan sulfate-modified DNA origami shells." ACS nano 16.12 (2022): 20002-20009.

    … VLPs were purchased from Creative Biostructure

    Related Services/Products:

    HPV16 VLP (L1 Proteins)

  12. Lodaya, Rushit N., et al. "A Self-Emulsified Adjuvant System Containing Alpha-Tocopherol Induced Higher Neutralizing Antibody Responses than a Squalene Only Emulsion Against a Recombinant Cytomegalovirus (CMV) Pentamer Antigen." (2022).

    … To understand the morphology of the oil droplets in SE-AS44 compared to AS03, we collaborated with Creative Biostructure (Shirley, NY) to obtain cryo-EM images and size analysis for …

    Related Services/Products:

    Particle Morphology Analysis

  13. Kim, Tae Gyun, et al. "Yeast nicotinate-nucleotide pyrophosphorylase in complex with its ligand: Crystallization and Preliminary structural approaches." bioRxiv (2022): 2022-11.

    … Apo NMnPP protein was initially crystallized using various screening kits from commercial company as Hampton Research, Creative Biostructure

    Related Services/Products:

    Optimization of Screening Kits and Reagents

  14. Goc, Anna, et al. "Linoleic acid binds to SARS-CoV-2 RdRp and represses replication of seasonal human coronavirus OC43." Scientific Reports 12.1 (2022): 19114.

    … SPR binding assay, which measures binding affinity KD as well kinetic parameters ka and kd of human RdRp protein, with LA as the ligand, was utilized, where RdRp protein was printed onto the chip and the analyte was LA at different concentrations (Creative Biostructure, Shirley, NY) … … It is a complex structure of SARS-CoV-2 RNA polymerase with double-strand RNA fragments (Creative Biostructure, Shirley, NY) …

    Related Services/Products:

    Surface Plasmon Resonance (SPR) Molecular Docking

  15. Weissman, Alex D. "AI in Proteomics: A Comparison Between Crystallographic and in silico Methods of Protein Modeling." (2022).

    … Our purified samples of NSP4 were then sent to Creative Biostructure for crystallization condition determination …

    Related Services/Products:

    X-ray Crystallography Services

  16. Yang, Quan-En, et al. "Rapid quality control assessment of adeno-associated virus vectors Via stunner." GEN Biotechnology 1.3 (2022): 300-310.

    … Empty versus full viral particle assays by TEM were performed by Creative Biostructure

    Related Services/Products:

    Cryo-EM for Viral Particle Identification and Characterization

  17. Lukose, Jijo, Santhosh Chidangil, and Sajan D. George. "Optical technologies for the detection of viruses like COVID-19: Progress and prospects." Biosensors and Bioelectronics 178 (2021): 113004.

    Creative Biostructure has been using their commercial SPR systems to evaluate the binding affinity between SARS-CoV-2 S protein and human ACE2 receptors. …

    Related Services/Products:

    COVID-19 VLP (S; GFP Protein)

  18. Andronico, Luca A., et al. "Sizing extracellular vesicles using membrane dyes and a single molecule-sensitive flow analyzer." Analytical chemistry 93.14 (2021): 5897-5905.

    … For selection of membrane dye, we used big liposomes (B-Lipo, from Creative Biostructure; DOPC:CHOL 55:45 mol/mol) whose distribution was centered at 130 nm …

    Related Services/Products:

    Non-Fluorescent DOPC/CHOL Liposomes (300nm)

  19. Al-shubaily, Fawzia A., and Maryam H. Al-Zahrani. "Characterization and Fine Structure of Exosomes." Role of Exosomes in Biological Communication Systems (2021): 27-75.

    Creative Biostructure provides a sensitive technology for exosome characterization to gain more information and accelerating the use of exosome biology in diagnostic tests or clinical …

    Related Services/Products:

    Exosome Characterization Services

  20. Alejaldre, Lorea, Joelle N. Pelletier, and Daniela Quaglia. "Methods for enzyme library creation: Which one will you choose? A guide for novices and experts to introduce genetic diversity." BioEssays 43.8 (2021): 2100052.

    … Other companies that offer library generation services include Creative Biostructure

    Related Services/Products:

    Custom Library Design and Construction Service

  21. Albadari, Najah, et al. "Synthesis and biological evaluation of selective survivin inhibitors derived from the MX-106 hydroxyquinoline scaffold." European Journal of Medicinal Chemistry 224 (2021): 113719.

    … We are currently working with a CRO (Creative Biostructure, Inc) to optimize the crystallization condition in order to obtain the crystal structures of survivin protein in complexes with this …

    Related Services/Products:

    X-ray Crystallography Services

  22. Liang, Chenyu, et al. "Exosomes of human umbilical cord MSCs protect against hypoxia/reoxygenation-induced pyroptosis of cardiomyocytes via the miRNA-100-5p/FOXO3/NLRP3 pathway." Frontiers in Bioengineering and Biotechnology 8 (2021): 615850.

    … Extracted exosomes were checked using transmission electron microscopy (TEM) (MagHelix, Creative Biostructure, Shirley, NY) …

    Related Services/Products:

    Particle Morphology Analysis

  23. Shewell, Lucy K., et al. "All major cholesterol-dependent cytolysins use glycans as cellular receptors." Science advances 6.21 (2020): eaaz4926.

    … We thank Creative Biostructure (NY, USA) for protein chemical shift assignment …

    Related Services/Products:

    Protein Thermal Shift Assay (PTSA)

  24. Bickmore, Diana C., and John J. Miklavcic. "Characterization of extracellular vesicles isolated from human milk using a precipitation-based method." Frontiers in nutrition 7 (2020): 22.

    … Fatty acid analysis was performed by Creative Biostructure (Shirley, NY USA) …

    Related Services/Products:

    Exosome Analysis Services

  25. Madrigal, Jasmine L., and Melissa K. Jones. "Quantifying human norovirus virus-like particles binding to commensal bacteria using flow cytometry." JoVE (Journal of Visualized Experiments) 158 (2020): e61048.

    … VLP Creative Biostructure CBS-V700 human norovirus virus like particle, VLPs were generated using the baculovirus system and resuspended in phosphate buffered saline with 10% …

    Related Services/Products:

    Norovirus GII.3 VLP (VP1 Protein)

  26. Biosystems, Emerald. "Products or services in software, drug discovery or protein production, purification and analysis." Nature 465 (2010): 10.

    Creative Biostructure Services to obtain and analyse crystallographic and NMR structures of macromolecules …

    Related Services/Products:

    X-ray Crystallography Services NMR Spectroscopy Services

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