Citations
Publications, Patents, and Book Chapters Citing Our Work
We provided high-quality service to numerous customers. A long list of papers have been published in Peer-reviewed Publications journals and a lot of patent applications have been approved or in process with custom products or services from us. Below are some selected patents and papers to give you an idea of how our products and custom services have been applied as part of leading edge in life science research in academia and industry. These publications are sorted according to different divisions of our company.
| Title | Author | Year | Journal | Description | Related Services/Products |
|---|---|---|---|---|---|
| Nutritional supplement containing a nuclear fraction of bovine thymus gland increases the circulating levels of spermidine | Surzenko N, Dominique A, et al. | 2025 | Plos one | … We would like to thank Creative Biostructure for their help in detecting and characterizing the liposomes and their content … |
Cryo-EM for Particle Morphology Analysis High-Performance Liquid Chromatography (HPLC) |
| Advances in magnetic affinity-based isolation/detection of exosomes for robust diagnostics | Solovicová V, Ďatková A, et al. | 2025 | Microchimica Acta | … Isolation of exosomes using microfluidic-based devices can be performed in a form of a service provided by the companies Creative Biostructure … | Microfluidics-Based Exosome Isolation Service |
| Pharmaceutical Chemistry Innovations | FATIMA T, SHABBIR S. | 2025 | Advances in Chemical Sciences | … QSAR Analysis: Creative Biostructure Drug Discovery … | QSAR Analysis |
| A VLPs based vaccine protects against Zika virus infection and prevents cerebral and testicular damage | Côrtes N, Lira A, et al. | 2025 | npj Vaccines | … The QβVLPs construction was made by Creative Biostructure (USA)… | Virus-like Particle Construction |
| Nanotechnology for the Efficacious Delivery of Medicinal Cannabis and Pharmaceutical Medicines | Vitetta L, Henson J D, et al. | 2025 | Pharmaceuticals | … Creative Biostructure, Shirley, NY, USA Lipo-308C [CBD] Cannabis sativa extract… | Active Cannabis Sativa Extract Liposome(Lipo-308C) |
| Extracellular vesicle miRNA signatures in pediatric onset-multiple sclerosis and obesity-driven immune and metabolic dysregulation | Hade M D, Reátegui E, et al. | 2025 | medRxiv | … RNA isolation, miRNA sequencing and bioinformatics were conducted by Creative Biostructure (Shirley, NY, USA)… | Exosomal Small RNA and miRNA Sequencing Service |
| Effects of Lipid Headgroups on the Mechanical Properties and In Vitro Cellular Internalization of Liposomes | Xu J, Adepoju S, et al. | 2025 | Langmuir | … Liposome Applications, Creative Biostructure… | Liposome Applications |
| A Novel and Reliable Analysis Method Utilizing Hennosides to Improve the Quality Assessment of Lawsonia inermis L. Material Used in Cosmetic Formulations | Dallmann N, Vill V, Straske F. | 2025 | Cosmetics | … All NMR experiments were performed by Creative BioStructure (Shirley, NY, USA)… | NMR Spectroscopy Services |
| Unlocking the Secrets of Protein Misfolding: AlphaFold’s Role in Cardiovascular Disease | Leyva R S. | 2024 | Berkeley Scientific Journal | … X-ray crystallography process: From crystal to protein model. Creative Biostructure… | X-ray Crystallography Platform |
| Evolution of the clinical-stage hyperactive TcBuster transposase as a platform for robust non-viral production of adoptive cellular therapies | Skeate J G, Pomeroy E J, et al. | 2024 | Molecular Therapy | … Plasmids containing individual point mutations were obtained from Creative Biostructure from a failed attempt to shuffle the mutations… | Custom Library Design and Construction Service |
| Nanodisc assembly from bacterial total lipid extracts | Llewellyn, Trent R., et al. | 2024 | Chemistry and Physics of Lipids | … In collaboration with Creative BioStructure (Shirley, NY, USA), the FEI Talos F200C Cryo-Transmission Electron Microscope was used to analyze one nanodisc sample … | Cryo-EM for Particle Morphology Analysis |
| Multiplexed electrical detection of whole viruses from plasma in a microfluidic platform | Jankelow, Aaron, et al. | 2024 | Analyst | … B19V virus-like particles (VLPs) (Cat# CBS-V088-C) were obtained from Creative BioStructure … | Parvovirus B19 VLP (VP1, VP2) Co-Capsid |
| Offline preparative separation methods based on electromigration: An overview and current trends | Hrušková, H.,Řemínek, R. and Foret, F. | 2024 | TrAC Trends in Analytical Chemistry | … Commercial free-flow electrophoretic instruments, e.g., Free-Flow electrophoresis systems marketed by FFE Service GmbH (Feldkirchen, Germany) or Creative BioStructure (Shirley, NY, USA) … | Mempro™ Free Flow Electrophoresis (FFE) |
| APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation | Marino, Claudia, et al. | 2024 | Alzheimer's & Dementia | ... Recombinant Fab region including the complementarity-determining regions (CDRs) of the 7C11.chIgG1 antibody was produced as fee-for-service by Creative BioStructure (Shirley, NY, USA) ...Binding kinetics between the purified Fab-7C11 protein and recombinant ApoE4 were quantified in PBS solution using a Biacore 3000 instrument (GE Healthcare) as a fee-for-service with Creative BioStructure and according to previously published procedures ...We resolved the three-dimensional crystal structure of purified 7C11.IgGFab protein as a fee-for-service with Creative BioStructure … | Custom Protein Production, Surface Plasmon Resonance (SPR), X-ray Crystallography Services |
| A self-adjuvanted VLPs-based Covid-19 vaccine proven versatile, safe, and highly protective | Vuitika, Larissa, et al. | 2024 | Scientific Reports | … synthetic E. coli plasmid of the QβVLPs was constructed by Creative BioStructure (Ramsey Road Shirley, NY 11967, USA), cloning the CP gene from Qβ bacteriophage into pET28a(+) without a 6x-His tag ... | Virus-like Particle Construction |
| Initial Exploration of the In Vitro Activation of GLP-1 and GIP Receptors and Pancreatic Islet CellProtection by Salmon-Derived Bioactive Peptides | Currie, C., Bjerknes, C. and Framroze, B. | 2024 | Marine Drugs | … Peptide fractionation was undertaken by Creative BioStructure (45–1 Ramsey Road, Shirley, New York, 11967, USA) ... | Protein Purification |
| Marine-derived sea urchin compounds as potential anti-cancer drug candidate against colorectal cancer: In silico and in vitro studies | Molla, M.H.R. and Aljahdali, M.O. | 2023 | Saudi Journal of Biological Sciences | ... Easily predicting the hydrophobicity, solubility, permeability, etc. of substances and applying predictive models for blood–brain barrier (BBB) permeability, medication bioavailability, cytochrome P450, hERG toxicity, and more are possible using Creative Biostructure … | ADME-Tox Modeling and Prediction |
| Purification, crystallization, and preliminary structural analysis of multivalent immunogenic effector protein-anchored SARS-CoV-2 RBD | Kwon, T.H. and Kim, T.G. | 2023 | bioRxiv | … Crystallization BmRecA-RBD protein was initially crystallized using various screening kits from commercial company as Hampton Research, Creative BioStructure … | Optimization of Screening Kits and Reagents |
| Inhibition of α-hemolysin activity of Staphylococcus aureus by theaflavin 3, 3’-digallate | Goc, Anna, et al. | 2023 | Plos one | … To determine binding affinity of native Hla with TF3, SPR binding assay was performed (Creative BioStructure, Shirley, NY)… | Surface Plasmon Resonance (SPR) |
| Phytochemicals and micronutrients in suppressing infectivity caused by SARS-CoV-2 virions andseasonal coronavirus HCoV-229E in vivo | Goc, Anna, et al. | 2023 | European Journal of Microbiology and Immunology | … SARS-CoV-2 viral like particles (VLPs) were obtained from Creative BioStructure (Shirley, NY, USA) … | SARS-CoV-2 VLP Products |
| A novel mechanism of herbicide action through disruption of pyrimidine biosynthesis | Kang, IL-Ho, et al. | 2023 | Proceedings of the National Academy of Sciences | … Creative BioStructure (Shirley, NY) provided the X-ray crystallographic support … | X-ray Crystallography Services |
| A Self-Emulsified Adjuvant System Containing the Immune Potentiator Alpha Tocopherol Induces Higher Neutralizing Antibody Responses than a Squalene-Only Emulsion When Evaluated with a Recombinant Cytomegalovirus (CMV) Pentamer Antigen in Mice | Lodaya, Rushit N., et al. | 2023 | Pharmaceutics | … To understand the morphology of the oil droplets in SE-AS44 compared to AS03, we collaborated with Creative BioStructure (Shirley, NY, USA) to obtain cryo-EM images and size … | Cryo-EM for Particle Morphology Analysis |
| A Review on Liposomes as a Drug Delivery System | Somasundaram, Dr N. | 2023 | International Journal of Pharmacy and Analytical Research(IJPAR) | ... Known for high performance and efficient development in liposome delivery systems, Creative BioStructure has extendedthe applications into the cosmetic industry … | Liposome Products |
| Dual-clamped one-pot SERS-based biosensors for rapid and sensitive detection of SARS-CoV-2 using portable Raman spectrometer | Kaladharan, Kiran, et al. | 2023 | Sensors and Actuators B: Chemical | … SARS-CoV-2 VLP protein was obtained from Creative BioStructures (New York, USA)... | SARS-CoV-2 VLP Products |
| Broad-spectrum virus trapping with heparan sulfate-modified DNA origami shells | Monferrer, Alba, et al. | 2022 | ACS nano | … VLPs were purchased from Creative BioStructure … | HPV16 VLP (L1 Proteins) |
| Yeast nicotinate-nucleotide pyrophosphorylase in complex with ligand: crystallization and preliminary structural approaches | Kim, Tae Gyun, et al. | 2022 | Biodesign | … Apo NMnPP protein was initially crystallized using various screening kits from commercial company as Hampton Research, Creative BioStructure … | Optimization of Screening Kits and Reagents |
| Linoleic acid binds to SARS-CoV-2 RdRp and represses replication of seasonal human coronavirus OC43 | Goc, Anna, et al. | 2022 | Scientific Reports | ... SPR binding assay, which measures binding affinity KD as well kinetic parameters ka and kd of human RdRp protein, withLA as the ligand, was utilized, where RdRp protein was printed onto the chip and the analyte was LA at different concentrations (Creative Biostructure, Shirley, NY) ...It is a complex structure of SARS-CoV-2 RNA polymerase with double-strand RNA fragments (Creative BioStructure, Shirley, NY) … | Surface Plasmon Resonance (SPR), Molecular Docking |
| AI in Proteomics: A Comparison Between Crystallographic and in silico Methods of Protein Modeling | Weissman, Alex D. | 2022 | Honors Theses | … Our purified samples of NSP4 were then sent to Creative BioStructure for crystallization condition determination … | X-ray Crystallography Services |
| Rapid quality control assessment of adeno-associated virus vectors Via stunner | Yang, Quan-En, et al. | 2022 | GEN Biotechnology | … Empty versus full viral particle assays by TEM were performed by Creative BioStructure … | Cryo-EM for Viral Particle Identification and Characterization |
| Nanoliposomes, from food industry to nutraceuticals: Interests and uses | Bondu, C. and Yen, F.T. | 2022 | Innovative Food Science & Emerging Technologies | … which manufactures food supplements from marine oil rich in omega 3, as well as Creative BioStructure which custom produces liposomes … | Liposome Production |
| Optical technologies for the detection of viruses like COVID-19: Progress and prospects | Lukose, J., Chidangil, S. and George, S.D. | 2021 | Biosensors and Bioelectronics | … Creative BioStructure has been using their commercial SPR systems to evaluate the binding affinity between SARS-CoV-2 S protein and human ACE2 receptors … | Surface Plasmon Resonance (SPR) |
| Characterization and fine structure of exosomes | Al-shubaily, F.A. and Al-Zahrani, M.H. | 2021 | Role of Exosomes in Biological Communication Systems | … Creative BioStructure provides a sensitive technology for exosome characterization to gain more information and accelerating the use of exosome biology in diagnostic tests or clinical … | Exosome Characterization Services |
| Methods for enzyme library creation: Which one will you choose? A guide for novices and experts to introduce genetic diversity | Alejaldre, L., Pelletier, J.N. and Quaglia, D. | 2021 | BioEssays | … Other companies that offer library generation services include Creative BioStructure … | Custom Library Design and Construction Service |
| Sizing extracellular vesicles using membrane dyes and a single molecule-sensitive flow analyzer | Andronico, Luca A., et al. | 2021 | Analytical chemistry | … For selection of membrane dye, we used big liposomes (B-Lipo, from Creative BioStructure; DOPC:CHOL 55:45 mol/mol)whose distribution was centered at 130 nm ... | Non-Fluorescent DOPC/CHOL Liposomes (300nm) |
| Synthesis and biological evaluation of selective survivin inhibitors derived from the MX-106 hydroxyquinoline scaffold | Albadari, Najah, et al. | 2021 | European Journal of Medicinal Chemistry | … We are currently working with a CRO (Creative BioStructure, Inc) to optimize the crystallization condition in order to obtain the crystal structures of survivin protein in complexes with this … | X-ray Crystallography Services |
| Exosomes of human umbilical cord MSCs protect against hypoxia/reoxygenation-induced pyroptosis of cardiomyocytes via the miRNA-100-5p/FOXO3/NLRP3 pathway | Liang, Chenyu, et al. | 2021 | Frontiers in Bioengineering and Biotechnology | … Extracted exosomes were checked using transmission electron microscopy (TEM) (MagHelix, Creative BioStructure, Shirley, NY) … | Cryo-EM for Exosome Characterization |
| All major cholesterol-dependent cytolysins use glycans as cellular receptors | Shewell, Lucy K., et al. | 2020 | Science advances | … We thank Creative BioStructure (NY, USA) for protein chemical shift assignment … | NMR Spectroscopy Services |
| Characterization of extracellular vesicles isolated from human milk using a precipitation-based method | Bickmore, D.C. and Miklavcic, J.J. | 2020 | Frontiers in nutrition | … Fatty acid analysis was performed by Creative BioStructure (Shirley, NY USA) … | Exosome Analysis Services |
| Quantifying human norovirus virus-like particles binding to commensal bacteria using flow cytometry | Madrigal, J.L. and Jones, M.K. | 2020 | J Vis Exp | … VLP Creative BioStructure CBS-V700 human norovirus virus like particle, VLPs were generated using the baculovirus system and resuspended in phosphate buffered saline with 10% … | Norovirus GII.3 VLP (VP1 Protein) |
| Machine learning and big scientific data | Hey, Tony, et al. | 2020 | Philosophical Transactions of the Royal Society A | … A schematic of the single-particle reconstruction cryoEM pipeline. Image thanks to Creative BioStructure … | Single Particle Analysis (SPA) |
| Cryo-EM for small molecules discovery, design, understanding, and application | Scapin, G., Potter, C.S. and Carragher, B. | 2018 | Cell chemical biology | … Commercial Options for Cryo-EM Imaging and Supplies … Creative BioStructure … | Cryo-Electron Microscopy (Cryo-EM) Services |
| Products or services in software, drug discovery or protein production, purification and analysis | Biosystems, E. | 2010 | Nature | … Creative BioStructure Services to obtain and analyse crystallographic and NMR structures of macromolecules ... | X-ray Crystallography Services, NMR Spectroscopy Services |
