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Proteins are crucial executors in various biological processes. To understand how specific proteins regulate corresponding biological processes, we need to investigate many aspects of proteins, such as localization, modification, interaction, function, and three-dimensional (3D) structure of proteins. Generally, obtaining high purity target protein is the prerequisite for protein structural analysis. For different downstream applications and proteins with diverse properties, different protein production techniques are needed to obtain high-quality target proteins.
Creative Biostructure develops appropriate gene-to-protein approaches for different protein production projects, which is customizable through working directly with our team of experienced scientists. We support every step of your target protein production, including but not limited to, gene synthesis, molecular cloning, protein expression, protein purification, protein modification, mutagenesis, and characterization.
Over the past decade, Creative Biostructure has established various expression systems to produce recombinant proteins, including high-performance cell-based expression systems as well as cell-free expression systems. Our technology platform for protein purification covers advanced chromatography.
Given the important roles of membrane proteins in cell function and the fact that membrane proteins remain the main focus for new drug discovery, our membrane protein platform has developed several efficient membrane protein expression systems and protein purification approaches to handle the dilemmas of membrane protein production and characterization.
Following optimal expression and purification of your protein of interest, Creative Biostructure guarantees precise determination of the native target structures with medium or high resolution. Based on thorough structural analysis, we further offer antibody development, drug discovery and vaccine formulation developments. Please feel free to contact us for more information or a detailed quote.