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Membrane proteins include transmembrane proteins that span across the membrane, Monotypic/peripheral membrane proteins that attached to the lipid bilayer or other integral proteins and peptide. The reason that membrane proteins studies are extremely important is that they are targets of over 50% of all modern drugs. It is estimated that 20-30% of all genes in most genomes encode membrane proteins. However, such proteins are inherently difficult to purify and characterize. The production of membrane protein is an urgent issue to handle with and optimize. Backed by a team with extensive experience in membrane protein production, Creative Biostructure can express and purify membrane proteins that are currently unavailable in the market (e.g., GPCR, ion channels, transporters, enzymes and viral targets).
Following is a list of membrane protein production provided by Creative Biostructure.
Transmembrane Protein Production | |||
5-Lipoxygenase-Activating Protein ABC Transporters ACBP Amyloid beta (A4) Bcl-2 Inhibitors BNIPs CAAX protease Cytochromes P450 E-NPPs EPHA1 EPHA2 EPHA3 EPHA4 Fatty Acid Desaturases Gamma secretase Glucose transporter Glycophorins GPCR HER2/ErbB2 HER3/ErbB3 HER4/ErbB4 HSD-11β | Hypoxia-induced Proteins Immunoglobulins Insulin receptor Integrins Ion channel MAPEG MFS MinK Family MPPs Peptidase AD Peptidase Family M48 Peptidase MA Protein Jagged Receptor-type Kinases SNARE Complex Sulfatases TNF receptor Transmembrane Proteins 14 Transporter TROBP VEGF receptors | Aldehyde Dehydrogenases | |
Monotypic/Peripheral Protein Production | |||
Alpha/Beta-Hydrolase Annexins Bet V1-Like Protein C1 Domain-Containing Protein C2 Domain-containing Protein CoA-Dependent Acyltransferases CRAL-TRIO Domain-Containing Protein DNase I-like protein Fibrinogen | FYVE/PHD Zinc Finger Protein | Phosphatidylinositol 3-/4-Kinase | |
Membrane Protein Peptides Production | |||
Amyloid Beta-sheet Peptides Membrane Anchor Helices of Peripheral Proteins | Peptide Fragments of Transmembrane Protein | Peptide fragments of water-soluble proteins |
Our scientists will assist you in all project stages evaluation, planning and execution. Each project is tailored to the customer’s specifications of scale, purity, analytical characterization and activity. We help our customers plan their projects in the most cost efficient manner. Please feel free to contact us for a detailed quote.
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