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Scientists at Creative Biostructure have successfully developed exosome/microvesicle products derived from different sources, which have diverse applications in exosome-based research, reflecting the functional status of their parent cells. Our range of products includes exosomes isolated from cancer cell lines, exosomes isolated from stem cell lines, exosomes isolated from immune-related cell lines, exosomes isolated from general cell lines, exosomes isolated from body fluids, fluorescent exosomes/microvesicles, as well as lyophilized microvesicles. Before proceeding with exosome engineering, it is crucial for you to choose the appropriate exosomes as a starting point of research.
Exosomes are endosomal-derived vesicles containing complex nucleic acids, proteins, lipids, and metabolites. They play a key role in cell-to-cell communication and signal transduction and are secreted in various biological fluids including cerebrospinal fluid, saliva, ascites, urine, and serum amongst others. Exosomes are small (approximately 40-160 nm in diameter, 100 nm on average) with a distinctive bilipid protein structure. They can carry and exchange a variety of cargos between cells and are used as non-invasive biomarkers for several diseases. Due to their unique characteristics, exosomes are considered the best biomarkers for cancer diagnosis. Exosomes derived from various sources have been used in research related to the prognosis and diagnosis of a variety of diseases including cardiovascular and regenerative diseases, arthritis, diabetes mellitus, neurological diseases as well as cancers.
Figure 1. Hallmarks of exosomes. (Kalluri R, et al., 2020)
Creative Biostructure has been and will always support researchers in finding the best solutions. We start to provide off-the-shelf exosome products that are ready for immediate worldwide delivery. Additionally, our scientists are ready to offer a complete set of services to support your exosome-associated research, such as exosome isolation and purification, exosome analysis and characterization and customizable exosomes for specific downstream applications.
We also offer services to support your exosome research, from isolation to characterization and assay. Please feel free to contact us for further information or a detailed quote.