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01
Identity & composition
Match the virus, strain or serotype, structural proteins, and displayed antigen to the biological question.
VLP Products for
Research & Assay Development
Explore virus-like particle products by virus family, virus name, and catalog number. Compare composition and expression source to find the right starting point for your research.
Fundamentals
What Are Virus-Like Particles?
Virus-like particles (VLPs) are assemblies of viral structural proteins that resemble aspects of a virus without the complete viral genome needed for autonomous replication. Their architecture can present repeated antigenic features for virology, immunization, and antibody research.
Creative Biostructure offers VLP products with sources including recombinant E. coli, yeast, insect cells, and HEK293 cells. Composition and source vary by product; a shared virus name does not make two constructs interchangeable.
VLP portfolio
Explore the VLP portfolio
01
COVID-19 Related VLP Products
Explore SARS-CoV-2-related constructs, including products with different structural protein combinations and reporter formats.
Review COVID-19 products →02
Off-The-Shelf VLP Products
Browse catalog VLP products across multiple viruses and expression sources. Check the individual product specifications for your application.
Browse catalog products →Browse by Virus Families
Choose a catalog family to view its product listings.
Alphaflexiviridae
Arenaviridae
Arteriviridae
Birnaviridae
Bromoviridae
Bunyaviridae
Caliciviridae
Carmotetraviridae
Circoviridae
Coronaviridae
Dicistroviridae
Filoviridae
Flaviviridae
Hepadnaviridae
Hepeviridae
Herpesviridae
Leviviridae
Matonaviridae
Nodaviridae
Orthomyxoviridae
Papillomaviridae
Papovaviridae
Paramyxoviridae
Parvoviridae
Picornaviridae
Pneumoviridae
Polyomaviridae
Potyviridae
Reoviridae
Retroviridae
Rhabdoviridae
Secoviridae
Togaviridae
Tombusviridae
Tymoviridae
Virus name finder
Find your virus of interest
Search the virus-name directory or browse A–Z. For a catalog number or product-specific keyword, open the complete VLP catalog.
Search controls are unavailable. You can still browse all virus-name links below or open the complete catalog.
107 virus names
Acinetobacter
phage
Adeno-associated
virus
African horse
sickness virus
Alfalfa mosaic
virus
Alternanthera mosaic
virus
Avian Flu virus
Bacteriophage MS2
Bacteriophage Qβ
Betanodavirus
Bluetongue virus
Bovine leukemia
virus
Bovine
papillomavirus
Bunyamwera virus
Canine distemper
virus
Canine parvovirus
Chikungunya virus
Cowpea chlorotic
mottle virus
Cowpea mosaic
virus
Coxsackievirus
Cytomegalovirus
Dengue virus
Ebola virus
Enterovirus 71
Epstein-Barr
virus
Equine
infectious anemia virus
Foot-and-mouth
disease virus
Grapevine fanleaf
virus
H1N1
H3N2
H5N1
H5N2
H5N8
H7N1
H7N2
H7N3
H7N7
H7N9
H9N2
Hamster
polyomavirus
Hantaan virus
Hendra virus
Hepatitis B virus
Hepatitis C virus
Hepatitis delta
virus
Hepatitis E virus
Human bocavirus
Human endogenous
retrovirus
Human
immunodeficiency virus
Human
metapneumovirus
Human
papillomavirus
Human parainfluenza
virus
Human T-cell
leukemia virus
Infectious
bronchitis virus
Infectious
bursal disease virus
Influenza A virus
Influenza virus
Japanese
encephalitis virus
John Cunningham
virus
Johnson
grass chlorotic stripe mosaic virus
Junin virus
Lassa virus
Maize rayado fino
virus
Marburg virus
Mayaro virus
Measles virus
Mouse hepatitis
virus
Mouse mammary tumor
virus
Mumps virus
Murine leukemia
virus
Murine
polyomavirus
Murine
respirovirus
Nervous necrosis
virus
Newcastle disease
virus
Nipah virus
Norovirus
Norwalk virus
Omsk hemorrhagic
fever virus
O'nyong'nyong
virus
Oropouche virus
Papaya mosaic
virus
Parainfluenza
virus
Parvovirus B19
Physalis mottle
virus
Poliovirus
Porcine
circovirus
Porcine
reproductive and respiratory syndrome virus
Providence virus
Rabbit
hemorrhagic disease virus
Rabies virus
Respiratory
syncytial virus
Rift valley fever
virus
Ross River virus
Rotavirus
Rous sarcoma
virus
Rubella virus
Salmonid
alphavirus
Sapporo-like
human calicivirus
SARS-CoV
SARS-CoV-2
Schmallenberg
virus
Semliki Forest
virus
Simian
immunodeficiency virus
Sudan virus
Swine vesicular
disease virus
Vesicular stomatitis
virus
West Nile virus
Zika virus
Selected catalog products
Examples from the Off-The-Shelf VLP Products collection. Open each product for its complete specifications.
| Cat. No. | Product Name | Source | Price |
|---|---|---|---|
| CBS-V641 | HPV16 VLP (L1 Proteins) | E. coli recombinant | |
| CBS-V946 | HPV39 VLP (L1 Proteins) | E. coli recombinant | |
| CBS-V065 | Chikungunya Virus VLP (E1, E2, C Proteins) | Mammalian cell recombinant | |
| CBS-V562 | Canine parvovirus virus VLP (VP2 Proteins) | Insect cell recombinant | |
| CBS-V952 | COVID-19 VLP (M; S; E Proteins) | Insect cell recombinant | |
| CBS-V926 | COVID-19 VLP (S; GFP Protein) | Pseudotyped lentivirus |
Availability, pricing, and delivery timing are confirmed during inquiry.
Selection guide
Choose a VLP
that
fits your experiment
Start with the biological question, then review the product-level evidence that matters to your assay.
02
Source & particle format
Review expression source, envelope status, and whether the entry is a conventional VLP or a pseudotyped particle.
03
Assay compatibility
Consider epitope accessibility, reporter requirements, conjugation needs, and compatibility with your assay buffer.
04
Product specifications
Check the listed concentration, formulation, storage, and available quality data. Requirements vary by catalog item.
Before requesting a quote
Share the catalog number or target virus, intended assay, required quantity, buffer constraints, and any essential characterization data. If a specification is not listed, request confirmation before ordering.
Production & characterization
From particle
assembly
to study-ready selection
VLP performance depends on how structural proteins assemble and how the resulting particles are purified and characterized. Aggregation, heterogeneity, and antigen presentation should be considered alongside protein identity.
Creative Biostructure provides VLP production and characterization services for projects that need support beyond catalog selection. Discuss particle morphology, size distribution, composition, or application-specific measurements with the team.
Explore custom VLP services →Case study
Supporting multiplexed virus detection in plasma
Creative Biostructure B19V VLPs supported a published microfluidic assay study by providing the parvovirus B19 target particles.
Research goal
Detect two viral targets in one platform
Jankelow and colleagues developed a microfluidic platform combining electrically distinguishable hydrogel beads with immunocapture to detect hepatitis A virus and parvovirus B19 particles in spiked plasma.
Our contribution
B19V VLPs · CBS-V088-C
B19V virus-like particles (VLPs) (Cat# CBS-V088-C) were obtained from Creative Biostructure. These particles served as the B19V targets in individual and multiplexed immunoassays. The workflow combined target capture on hydrogel beads with differential electrical counting.
Explore the B19V VLP productPublished outcome
Multiplexed electrical detection
The study demonstrated simultaneous capture and detection of both targets in plasma-spiking experiments, distinguishing target-positive samples from negative controls. The supplied VLPs enabled the B19V arm of this proof-of-concept workflow.
Research significance
Defined particles for assay development
Creative Biostructure contributed the B19V target material used to evaluate the microfluidic assay. The findings support a proof of concept for multiplexed electrical virus detection; the experiments do not establish clinical diagnostic performance.
Customer publication
Multiplexed electrical detection of whole viruses from plasma in a microfluidic platform
Jankelow, A., et al. (2024). Analyst, 149, 1190–1201. DOI: 10.1039/d3an01510f. Product attribution: Materials and methods, Sections 2.1 and 2.8.
Read the customer publicationResearch applications
Connect the particle to the research goal
The portfolio supports a range of research directions. Suitability depends on the selected construct and experimental validation.
Virus research
Study particle structure, assembly, or antigen presentation with an appropriate construct.
Therapeutic and imaging agents
Explore particle-based delivery or imaging concepts in research settings.
Vaccines
Investigate antigen display and immunogenicity in vaccine research.
Immunization for antibody elicitation
Select antigens for research immunization and antibody-generation workflows.
Phage and yeast display
Consider particle antigens in compatible display-based selection workflows.
Antibody screening by ELISA
Assess antibody recognition using a suitable particle antigen and assay controls.
Kinetic analysis of antibody binding by biosensor
Evaluate binding while accounting for multivalency and surface presentation.
Radioligand and fluorescent binding assays
Review labeling compatibility and signal requirements for the selected particle.
Frequently asked questions
What to know before selecting a VLP product
Product requirements depend on virus identity, particle composition, expression source, and intended assay. Review the available specifications or discuss a custom route with our scientists.
Start with the virus family or virus-name directory, then compare the catalog number, composition, and expression source. Select the construct that fits your assay rather than relying on the virus name alone.
No. Conventional VLPs are assembled viral structures without the complete genome needed for autonomous replication. Pseudotyped particles may contain reporter or other vector components and can have different entry and assay properties. Review the product description and handling requirements for each construct.
The VLP portfolio includes products from recombinant E. coli, yeast, insect cells, and HEK293 cells, among other listed sources. The expression source is product-specific; consult the individual catalog entry.
No. Antigen binding does not establish suitability for a cell-based neutralization assay. Such assays require a compatible entry or reporter system. Confirm the intended assay, reporter, and target-cell requirements with the technical team.
Review the individual product page for the specifications that are provided. Request confirmation of concentration, formulation, storage, particle characterization, purity, or residual nucleic-acid information when these are critical to your experiment. Do not assume identical specifications across products.
Yes. Send the target virus or catalog number, intended assay, required quantity, and any essential specifications through the inquiry page. The team can review catalog options or discuss a custom VLP project and confirm pricing and availability.
Publications
Published research using our VLP products
Explore customer publications citing Creative Biostructure VLP materials in viral detection, virus–host interaction, and particle-trapping research.
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01
View DOI ↗
Multiplexed electrical detection of whole viruses from plasma in a microfluidic platform
Jankelow, Aaron, et al. (2024). Analyst.
Creative Biostructure supplied B19V VLPs (CBS-V088-C), which were used as parvovirus B19 targets in the microfluidic detection experiments.
Parvovirus B19 VLP (VP1, VP2) Co-Capsid → -
02
View DOI ↗
Phytochemicals and micronutrients in suppressing infectivity caused by SARS-CoV-2 virions and seasonal coronavirus HCoV-229E in vivo
Goc, Anna, et al. (2023). European Journal of Microbiology and Immunology.
The study used SARS-CoV-2 virus-like particles obtained from Creative Biostructure in research on phytochemicals, micronutrients, and coronavirus infectivity.
SARS-CoV-2 VLP Products → -
03
View DOI ↗
Dual-clamped one-pot SERS-based biosensors for rapid and sensitive detection of SARS-CoV-2 using portable Raman spectrometer
Kaladharan, Kiran, et al. (2023). Sensors and Actuators B: Chemical.
The researchers obtained SARS-CoV-2 VLP protein from Creative Biostructure for a SERS-based biosensor study using a portable Raman spectrometer.
SARS-CoV-2 VLP Products → -
04
View DOI ↗
Broad-spectrum virus trapping with heparan sulfate-modified DNA origami shells
Monferrer, Alba, et al. (2022). ACS nano.
The authors reported purchasing VLPs from Creative Biostructure for research on virus trapping with heparan sulfate-modified DNA origami shells.
HPV16 VLP (L1 Proteins) → -
05
View DOI ↗
Quantifying human norovirus virus-like particles binding to commensal bacteria using flow cytometry
Madrigal, J.L. and Jones, M.K. (2020). J Vis Exp.
The protocol lists Creative Biostructure human norovirus VLPs (CBS-V700) among the materials used to quantify VLP binding to commensal bacteria by flow cytometry.
Norovirus GII.3 VLP (VP1 Protein) →
Resources
VLP guides and support knowledge
Browse practical background materials on VLP technology, virus families, production, and particle engineering.
Support
knowledge
MemPro™ Virus-like Particles (VLPs) Technology
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Mempro™ Virus Families for Virus-like Particles (VLPs)
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Mempro™ Virus-like Particles (VLPs) Production
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Mempro™ Virus-like Particles (VLPs) Application
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Mempro™ Virus-like Particles (VLPs) Characterization
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Mempro™ Virus-like Particles (VLPs) Modification
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