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VPS29 Protein Crystal(CBCRY38)

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Product Summary
Name VPS29 Protein Crystal
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Cat No.CBCRY38
FragmentFull length
Protein DescriptionVacuolar Protein Sorting Protein 29
BackgroundVPS29 belongs to a group of genes coding for vacuolar protein sorting (VPS) proteins that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene, Vps29, is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. Vps29 may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment.
Protein Classificationcytoplasmic protein
Structure Weight20531.90 Da
MethodX-Ray Diffraction
Resolution2.10Å
ReferenceWang, D., Guo, M., Liang, Z., Fan, J., Zhu, Z., Zang, J., Zhu, Z., Li, X., Teng, M., Niu, L., Dong, Y., Liu, P. (2005) Crystal Structure of Human Vacuolar Protein Sorting Protein 29 Reveals a Phosphodiesterase/Nuclease-Like Fold and Two Protein-Protein Interaction Sites. J.Biol.Chem. 280: 22962

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