MAD2 (mitotic arrest deficient 2) is one of the kinetochore protein present on the chromosome during cell division. It is involved in making sure all chromosomes are attached to the mitotic spindle before the beginning of anaphase.
Yang, M., Li, B., Liu, C.-J., Tomchick, D.R., Machius, M., Rizo, J., Yu, H., Luo, X. (2008) Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer. Plos Biol. 6: E50