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Product Summary
Fragment
Full length
Protein Description
Mitotic arrest deficient 2
Background
MAD2 (mitotic arrest deficient 2) is one of the kinetochore protein present on the chromosome during cell division. It is involved in making sure all chromosomes are attached to the mitotic spindle before the beginning of anaphase.
Protein Classification
Cell Cycle
Structure Weight
288687.00 Da
PDBID
2VFX
Method
X-Ray Diffraction
Resolution
1.95 Å
Ligand Chemical Component
Chloride ion, Magnesium ion, PE3, PE4, PEG
Reference
Yang, M., Li, B., Liu, C.-J., Tomchick, D.R., Machius, M., Rizo, J., Yu, H., Luo, X. (2008) Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer. Plos Biol. 6: E50
cDNALength
618