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SAT1 Protein Crystal(CBCRY21)

Product Summary
Name SAT1 Protein Crystal Download Datasheet
Background Spermidine/spermine N(1)-acetyltransferase (SSAT; EC is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the N(1)-acetylation of spermidine and spermine and, by the successive activity of polyamine oxidase, spermine can be converted to spermidine and spermidine to putrescine.
Molecular Description
Protein ClassificationTransferase
Structure Weight42238.60 Da
MoleculeDiamine acetyltransferase 1
Chain Length179 amino acids
Crystal Description
MMDB ID38382
MethodX-Ray Diffraction
Gene Information
Gene NameSAT1
SynonymsDC21; EC; KFSD; SAT; SSAT; SSAT-1;OTTHUMP00000023061; diamine N-acetyltransferase 1; diamine acetyltransferase 1; spermidine/spermine N1-acetyltransferase alpha; spermidine/spermine N1-acetyltransferase 1; Polyamine N-acetyltransferase 1; Putrescine acetyltransferase
UniProt IDP21673
Gene ID6303
Chromosome LocationXp22.1
Functionacyltransferase activity; diamine N-acetyltransferase activity; transferase activity
Reference Zhu, Y.Q., Zhu, D.Y., Yin, L., Zhang, Y., Vonrhein, C., Wang, D.C. (2006) Crystal structure of human spermidine/spermine N1-acetyltransferase (hSSAT): the first structure of a new sequence family of transferase homologous superfamily Proteins 63: 1127-1131

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