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PABPN1 Protein Crystal(CBCRY37)

Product Summary
Name PABPN1 Protein Crystal Download Datasheet
Background
Background Poly(A) binding protein, nuclear 1, also known as PABPN1, is required for progressive and efficient polymerization of poly(A) tails on the 3' ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm.
Molecular Description
Protein ClassificationRNA binding protein
Structure Weight43445.20 Da
Polymer1
MoleculePolyadenylate-binding protein 2
Chain Length96 amino acids
Crystal Description
PDB ID3B4M
MMDB ID61872
SourceE.coli
MethodX-Ray Diffraction
Resolution2.82Å
Gene Information
Gene NamePABPN1
SynonymsOPMD; PAB2; PABP2; poly(A) binding protein 2; poly(A) binding protein II; poly(A) binding protein, nuclear 1
UniProt IDQ86U42
Gene ID8106
Chromosome Location14q11.2-q13
Functionnucleotide binding; nucleic acid binding; RNA binding; protein binding
Reference
Reference Ge, H., Zhou, D., Tong, S., Gao, Y., Teng, M., Niu, L. (2008) Crystal structure and possible dimerization of the single RRM of human PABPN1 Proteins 71: 1539-1545

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