Creative Biostructure to Present at AACR Annual Meeting 2024 Creative Biostructure to Present at AACR Annual Meeting 2024 | April 5-10, 2024 | Booth #2953 Learn More > Close

EphA2 Protein Crystal(CBCRY49)

Inquiry
Product Summary
Name EphA2 Protein Crystal
Download Datasheet
Cat No.CBCRY49
FragmentEctodomain, Residues 27-534
Protein DescriptionEPH Receptor A2
BackgroundEphrin type-A receptor 2 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. It regulates cell adhesion and differentiation and also participates in UV radiation-induced apoptosis. Mutations in this gene are the cause of certain genetically-related cataract disorders.
Protein ClassificationReceptor
Structure Weight60679.26 Da
MethodX-Ray Diffraction
Resolution3.00 Å
Ligand Chemical ComponentCl-, NAG
ReferenceSeiradake E, Harlos K, Sutton G, Aricescu AR, Jones EY. An extracellular steric seeding mechanism for eph- ephrin signalling platform assembly. Nat.Struct.Mol.Biol. (2010) 17 p.398

Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Inquiry