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NTF3 with NGFR Protein Crystal(CBCRY18)

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Product Summary
Name NTF3 with NGFR Protein Crystal
Download Datasheet
Cat No.CBCRY18
FragmentEctodomain
Protein DescriptionNeurotrophin-3 complexed with NTR receptor
BackgroundNeurotrophins (NTs) are important regulators for the survival, differentiation and maintenance of different peripheral and central neurons. NTs bind to two distinct classes of glycosylated receptor: the p75 neurotrophin receptor (p75(NTR)) and tyrosine kinase receptors (Trks). Whereas p75(NTR) binds to all NTs, the Trk subtypes are specific for each NT.
Protein Classificationsignaling protein
Structure Weight63861.22 Da
MethodX-Ray Diffraction
Resolution2.6Å
Ligand Chemical ComponentN-Acetyl-D-Glucosamine
ReferenceGong, Y., Cao, P., Yu, H.J., Jiang, T. (2008) Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex. Nature 454: 789-793

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