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Product Summary
Fragment
UNP residues 167-254
Protein Description
Polyadenylate-binding Protein 2
Background
Poly(A) binding protein, nuclear 1, also known as PABPN1, is required for progressive and efficient polymerization of poly(A) tails on the 3' ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm.
Protein Classification
RNA binding protein
Structure Weight
43445.20 Da
PDBID
3B4M
Method
X-Ray Diffraction
Resolution
2.82Å
Reference
Ge, H., Zhou, D., Tong, S., Gao, Y., Teng, M., Niu, L. (2008) Crystal structure and possible dimerization of the single RRM of human PABPN1 Proteins 71: 1539-1545
cDNALength
288