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Based on the comprehensive biophysical characterization platform established through years of experience, scientists from Creative Biostructure are highly experienced and knowledgeable in the application of thermogravimetric analysis or thermal gravimetric analysis (TGA) on food, pharmaceuticals, polymers as well as many other materials.
TGA is a method of thermal analysis, in which the mass of the samples is measured against time or temperature while the temperature of the samples is programmed in a controlled atmosphere. This analytical technique is commonly employed in determing the composition of samples and predicting their thermal stability. From TGA analysis, we can provide information about chemical phenomena and physical phenomena, including chemisorptions, dehydration, decomposition, solid-gas reactions (e.g., oxidation or reduction), vaporization, sublimation, absorption, and desorption. In essense, TGA can assess the samples that exhibit weight loss or gain owing to decomposition, oxidation, or dehydration.
Figure 1. The diagram of a typical TGA system.
Typical applications of TGA include:
Creative Biostructure’s TGA instruments can be utilizied to ramp temperature from room temperature to 1000°C in different gas atmospheres such as nitrogen, air or other inert gases. In addition, sample weight can range from 1 mg to 150 mg, and the sensitivity of weight change is 0.01 mg.
Our MagHelix™ analytical methods for biophysical characterization of biomolecules include but are not limited to:
A. W. Coats and J. P. Redfern (1963). Thermogravimetric Analysis: A Review. Analyst, 88(1053): 906-924.
Thermogravimetric analysis. Wikipedia. https://en.wikipedia.org/wiki/Thermogravimetric_analysis.
X. Liu, and W. Yu, (2006). Evaluating the Thermal Stability of High Performance Fibers by TGA. J. Applied Polymer Sci., 99: 937-944.