Quantitative NMR Analysis of Chemical Substances

Quantitative nuclear magnetic resonance (qNMR) is a potential benchmark method for the determination of organic compounds, with many advantages including

• It is a direct analysis method (except for structural related impurities, there is no need for qualitative and quantitative analysis of impurities).
• Strong versatility.
• The analysis time is short.
• Non-destructive.

There is no need to obtain its own reference materials for the tested object (several traceable reference materials can support the traceability of all organic compounds).

Creative Biostructure can provide customers with quantitative analysis services for chemical components in organic compounds, inorganic compounds, polymers, natural products, pharmaceuticals, food ingredients, industrial chemicals, environmental samples, and biological liquids. We can test ¹H, ¹³C, ⁹F, ³¹P, ²⁹Si, and ¹⁷Q NMR spectra.

Our Approaches

• Purity analysis

We can analyze the purity of the sample by comparing the strengths of different signals in the NMR spectrum.

• Concentration measurement

By comparing the signal strengths of samples and standards with known concentrations, we can determine the concentration of compounds in the solution.

• Determination of molecular mass

The chemical shifts of atomic nuclei in nuclear magnetic resonance spectroscopy are influenced by the nuclear mass and its surrounding chemical environment. By analyzing the physical displacements of different nuclei in a molecule, we can determine the mass of the molecule.

Analyzable Samples

The samples we can analyze include but are not limited to

• Organic compounds such as alcohols, aldehydes, ketones, carboxylic acids, amines, and amides.
• Inorganic compounds, such as metal complexes, salts, and catalytic compounds.
• Polymers such as polyethylene, polystyrene, and polypropylene.
• Natural products such as proteins, nucleic acids, and carbohydrates.
• Drugs such as antibiotics, steroids, and antihistamines.
• Food ingredients such as vitamins, amino acids, and pigments.
• Industrial chemicals such as solvents, adhesives, and surfactants.
• Environmental samples such as water, soil, and air pollutants.
• Petroleum chemicals such as crude oil, gasoline, and diesel.
• Biological fluids such as blood, urine, and saliva.

Sample Delivery Requirements and Precautions

• Solid or liquid. 20-100mg in a plastic centrifuge tube.
• The sample is completely soluble in a common volatile solvent (water, toluene, DMSO, methanol, chloroform, etc.)

Workflow of Our qNMR Service

Why Select Us

• We mainly focus on research and development, analysis, and testing. Rich experience and wide range of services.
• Our testing cycle is short, the cost is low, and the data is scientific and accurate.
• We support nationwide on-site sampling and sample-sending testing services.
• We have multiple branch laboratories around the world.
• We have advanced testing equipment and a formal testing team.
• We provide perfect after-sales service.
• We will sign confidentiality agreements with customers and pay attention to protecting their privacy.

Creative Biostructure is committed to providing high-quality NMR analysis services to advance the life sciences fields. If you have any questions or needs, please contact us and our customer service staff will help you the first time.

Ordering Process