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Product Summary
Fragment
Full length
Protein Description
Serum Albumin
Background
3'-Azido-3'-deoxythymidine (AZT) is the first clinically effective drug for the treatment of human immunodeficiency virus infection. The drug interaction with human serum albumin (HSA) has been an important component in understanding its mechanism of action, especially in drug distribution and in drug-drug interaction on HSA in the case of multi-drug therapy.
Protein Classification
Lipid binding protein
Structure Weight
68485.53 Da
PDBID
3B9M
Method
X-Ray Diffraction
Resolution
2.70Å
Ligand Chemical Component
AZZ; Myristic acid; 2-hydroxybenzoic acid
Reference
Zhu, L., Yang, F., Chen, L., Meehan, E.J., Huang, M. (2008) A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography J.Struct.Biol. 162: 40-49
cDNALength
1674