Detection and Quantification of Monomer Content

Thermoplastic or thermosetting plastics (PE, PP, PET, PVC, PTFE), composite materials and polymer-based formulations (paint, glue, resin, varnish). NMR is very suitable for the analysis of residual monomers in these polymers and formulations. The characteristics of polymers are directly related to their composition and properties. Depending on the monomers used in the polymerization process, the characteristics of the polymer may change greatly. The residual monomers in the polymer reaction may be dangerous. Some monomers are toxic, and many monomers promote the early or accelerated degradation of the polymer. It is not conducive to product development and quality control.

As an expert in the field of nuclear magnetic resonance, scientists of Creative Biostructure can provide customers in various fields with residual monomer identification and content analysis services in multi-polymer systems through ¹H NMR and ¹³C NMR.

In addition to ¹H and ¹³C, the most commonly used analytical elements for the determination of organic polymers and small molecules, we can also analyze other elements, such as silicon (²⁹Si) and fluorine (¹⁹F). Due to the variety of sample introduction technologies in our laboratory, the residual monomer content of almost any sample can be determined.

Samples and Precautions

NMR technology uses powerful magnets, which means that the sample cannot contain iron or other magnetic additives. A sample of 10 to 50 mg is usually sufficient to obtain an NMR spectrum with an excellent signal-to-noise ratio.

Testable Products

• Bioabsorbable polymers (PLA, PLGA, PCL)
• Methyl methacrylate (MMA)
• Acrylic
• Polyphase copolymer of propylene
• Propylene random copolymer
• Propylene random terpolymer
• Ethylene-propylene-2-ethylene-5-n-borane (ENB) terpolymer
• Products with bisphenol A (BPA)

Using ¹³C NMR spectrum, we can determine the distribution of complete binary, triplet, tetrad, and pentad.

Service Applications

Follow the reaction process and final product through quantitative analysis of the monomer.

Identify the residual monomers in the formula and evaluate the safety of the product.

Ensure product integrity and meet quality control requirements.

The determination of residual monomer content is usually a part of comprehensive additive analysis and investigation.

Creative Biostructure is committed to providing high-quality NMR analysis services to advance the life sciences fields. If you have any questions or needs, please contact us and our customer service staff will help you the first time.

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