What are the key advantages of pre-assembled nanodiscs?

Pre-assembled nanodisc products offer a streamlined solution for membrane protein studies. They provide a ready-to-use platform, reducing preparation time and ensuring consistent results.

Can you elaborate on the compatibility of pre-assembled nanodiscs with common analytical techniques?

Pre-assembled nanodiscs are compatible with a range of analytical techniques, including NMR spectroscopy, circular dichroism, and various chromatographic methods. Their well-defined structure facilitates accurate analysis of membrane protein properties, allowing researchers to obtain detailed insights into structure, dynamics, and interactions.

What quality control measures are in place for pre-assembled nanodiscs?

Quality control measures for pre-assembled nanodiscs typically include rigorous testing of stability, homogeneity, and functionality. We can provide detailed QC data with each product batch.

What considerations should be kept in mind regarding the selection of MSPs?

Researchers should consider factors such as the size, charge, and topology of the target membrane protein when selecting membrane scaffold proteins. Tailoring the choice of MSP to match the characteristics of the protein of interest ensures optimal stabilization and functionality. Additionally, consulting literature and available protocols for recommended MSP-protein combinations can enhance experimental success.

Are there specific applications where assembled nanodiscs excel?

Assembled Nanodiscs excel in membrane protein studies, drug delivery systems, and structural biology due to their stability, customizable lipid composition, and compatibility with diverse biomolecules, offering researchers a reliable platform for robust and insightful results.

What is the pricing and are there bulk purchase discounts for Nanodiscs products?

Our pricing for Assembled Nanodiscs is transparent and competitive. For specific product pricing and potential bulk purchase or long-term collaboration discounts, contact our sales team directly for personalized solutions.

How can MSP benefit my research?

Membrane Scaffold Proteins (MSPs) play a vital role in stabilizing and organizing membrane proteins, facilitating structural and functional studies. By creating a stable environment, our products enhance research precision, leading to more reproducible and higher-quality findings.

What support accompany your membrane scaffold proteins?

In addition to our high-quality membrane scaffold proteins , we provide extensive technical support, documentation, and application resources. We aim to assist researchers throughout, from product selection to troubleshooting, ensuring a seamless integration of our products into your experiments.

Human MSP1D1 lyophilized protein with a his-tag(MSP-1001)

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Product Summary
Name	Human MSP1D1 lyophilized protein with a his-tag
	Download Datasheet
Cat No.	MSP-1001
Shortname	MSP1D1
Source	E.coli
Product Overview	Recombinant human membrane scaffold protein 1D1 was expressed in E.coli and purified by Ni-NTA.
Purity	>90%
Species	Human
Tag	His
Molecular Mass	25.30kDa
Storage	Stored lyophilized powder at -20°C. The reconstituted solution should be stored at 2-8°C and should be used up in several days.
Background	Nanodiscs are a new class of model membranes that are being used to solubilize and study a range of integral membrane proteins and membrane-associated proteins. The Nanodisc bilayer is bounded by a membrane scaffold protein coat that confers enhanced stability and a narrow particle size distribution. The nanodisc assembles from a mixture of full length membrane protein in detergent, phospholipid micelles and membrane scaffold protein upon removal of the detergent.
Reconstitution	Adding double distilled watwe to prepare a stock solution of 4mg/mL. This stock solution can be diluted further as required by the differnet application protocols.
Scaffold Diameter	9-11 nm
Formulation	Lyophilized from 20mM Tris pH 7.4, 100 mM NaCl, 0.5 mM EDTA.

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