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Product Summary
Product Overview
Ixabepilone (Azaepothilone B, BMS-247550, Ixempra, Aza-epothilone B) is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis. This product is a PEG modified pre-formulated liposome with Ixabepilone (BMS-247550) loaded. It is supplied ready to use in vitro or in vivo studies.
Lipid Composition
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Active Ingredients
Ixabepilone
Form
Liquid
Storage Buffer
292 mM sucrose, 0.5% DPBS (1X)
Concentration
2.5 mg/mL (± ~5%) (Concentration Ixabepilone); Lipid Concentration 60 mM
Stability
At least 1 month
Storage
2 °C to 8 °C (do not freeze), protect from light