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Product Summary
Source
Pseudotyped lentivirus
Virus Name
SARS-CoV-2
Virus Family
Coronaviridae
Composition
S-his, GFP
Purity
90%
Presentation
PBS
Description
It is the replication-incompetent particles in which the native, full-length COVID-19 S protein (with 6His-tag at its C-terminal) was pseudo-typed as the lentiviral particles’ surface envelope protein. The virus genome is not included. Instead it was replaced by a GFP under CMV promoter. It is mock lentivirus. This VLP binds to cells that express any S-protein binding receptor, like ACE2. When this binding occur, the VLP stay at surface of the cells and also can get into cells, then the GFP signal can be detected.