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Product Summary
Product Overview
1,2-Dioleoyl-sn–glycero-3-phosphoethanolamine (DLPE)-polyethylene glycol methoxy (DLPE-MPEG) is a linear heterobifunctional PEGylation reagent with an unsaturated DLPE phospholipid. It is a useful self-assembling reagent to prepare grafted or PEGylated liposome or micelle while also providing an amine group for bioconjugation. It is often used in targeted drug delivery with the lipid bilayer to improve drug solubility, the PEG to provide stealth property, extend circulation half-life and reduce non-specific protein binding or cell adhesion, and the amine group to bioconjugate targeting molecules including antibody, aptamer, protein, and peptide.
Purity
>95%
Application
Liposome production; Synthetic lipid
Form
Off-white/white solid or viscous liquid depends on molecule weight. Soluble in regular aqeous solution as well as most organic solvents
Storage
Store at -20 °C
Synonyms
DSPE-PEG(2000) Amine Lipids