Home Products STEALTH Liposomal Irinotecan HCl (2.0mg/mL)
STEALTH Liposomal Irinotecan HCl (2.0mg/mL)
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STEALTH Liposomal Irinotecan HCl (2.0mg/mL)

Catalog No. HSPC-066L

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Product Summary

Product Overview
Irinotecan HCl is loaded into PEGylated liposomes composed of HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) with ammonium gradient by the active loading approach. The liposomes are produced by the extrusion method. The product is of high quality with narrow particle size distribution and high drug encapsualtion efficiency.<br />Lipid composition: HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol)<br />Encapsulation efficiency:> 95% (typically 98%)<br />Mean particle size: 100 nm (80-110 nm)
Lipid Composition
HSPC; CHOL; mPEG2000-DSPE
Active Ingredients
Irinotecan HCl
Application
Liposome production; Synthetic lipid
Storage Buffer
Loading battery: 250 mM ammonium sulfate<br />External solution: 10% sucrose, 20 Mm HEPES, pH 7.0
Concentration
Lipid concentration: 20.0 mM<br />Iroinotecan HCl: 2.0 mg/mL
Stability
3 Month for unopened vials.
Storage
Store at 2-8 centigrade.
Synonyms
HSPC; hydrogenated phosphatidylcholine (Soy); CHOL; cholesterol; mPEG2000-DSPE