Home Products STEALTH Liposomal Topotecan HCl (2.0mg/mL)
STEALTH Liposomal Topotecan HCl (2.0mg/mL)
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STEALTH Liposomal Topotecan HCl (2.0mg/mL)

Catalog No. HSPC-067L

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Product Summary

Product Overview
Topotecan HCl is loaded into PEGylated liposomes composed of HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol) with ammonium sulfate gradient by the active loading approach. The liposomes are produced by the extrusion method. The product is of high quality with Narrow particle size distribution and high drug encapsualtion efficiency. <br />Lipid composition: HSPC/CHOL/mPEG2000-DSPE (50:45:5 mol/mol)<br />Encapsulation efficiency:> 95%<br />Mean particle size: 100 nm (80-110 nm)
Lipid Composition
HSPC/CHOL/mPEG2000-DSPE
Active Ingredients
Topotecan HCl
Application
Liposome production; Synthetic lipid
Storage Buffer
Loading battery: 250 mM ammonium sulfate<br />External solution: 10% sucrose, 20 Mm HEPES, pH 7.0
Concentration
Lipid concentration: 20.0 mM<br />Topotecan HCl: 2.0 mg/mL
Stability
3 Month for unopened vials.
Storage
Store at 2-8 centigrade.
Synonyms
HSPC; hydrogenated phosphatidylcholine (Soy); CHOL; cholesterol; mPEG2000-DSPE