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Product Summary
Product Overview
Rocaglamide (Roc-A), isolated from Aglaia species, is a potent inhibitor of heat shock factor 1 (HSF1) activation with IC50 of ~50 nM for HSF1. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also inhibits NF-?B activity. Rocaglamide exhibits anti-tumor activity. This product is a PEG modified pre-formulated liposome with Rocaglamide (Roc-A) loaded. It is supplied ready to use in vitro or in vivo studies.
Lipid Composition
/
Active Ingredients
Rocaglamide
Form
Liquid
Storage Buffer
292 mM sucrose, 0.5% DPBS (1X)
Concentration
4.0 mg/mL (± ~5%) (Concentration Rocaglamide); Lipid Concentration 60 mM
Stability
At least 1 month
Storage
2 °C to 8 °C (do not freeze), protect from light