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Creative Biostructure has developed an advanced Mempro™ Nanodisc analysis platform for a long time. With our experienced scientists hammered at Nanodisc resrarch for years, we provide customized Mempro™ electron paramagnetic resonance (EPR) sevice for Nanodisc analysis.
When the solid molecules reveal paramagnetism for their unpaired electron spins, transitions can be activated via using the magnetic field. Then electromagnetic energy is offered during this process, commonly in the range of microwave frequencies. The resulting absorption spectra are named as EPR or electron spin resonance (ESR). EPR has been applied as a powerful technique for the research of radicals formed in solid materials, because the radicals usually generated an unpaired spin on the molecule. The interaction of an electron spin and an exterior magnetic field lies on the magnetic moment connected with the spin, and the nature of an isolated electron spin is such that two and only two orientations are available.
Figure 1. Towards high-frequency, high-power pulsed EPR spectroscopy. (Takahashi, S. 2012)
Creative Biostructure provides other various Mempro™ nanodisc technology services, besides nanodiscs analysis. Please feel free to contact us for a detailed quote.
Takahashi, S. (2012). “Pulsed electron paramagnetic resonance spectroscopy powered by a free-electron laser”. Nature, 489(7416), 409-413.
Stepien, P.(2015). “Comparative EPR studies on lipid bilayer properties in nanodiscs and liposomes”. Biochimica et Biophysica Acta (BBA)-Biomembranes, 1848(1), 60-66.
Bayburt, T. H. (2010). “Membrane protein assembly into Nanodiscs”. FEBS letters, 584(9), 1721-1727.